For a long time considered geopolitical margins, cities along the Mexico–United States border are no longer just buffer zones — they are becoming real laboratories for binational innovation. In 2025, the evidence is clearer than ever: from Tijuana to Brownsville, and including Nogales and El Paso, these urban centers are taking the lead in testing public policies, urban technologies, and new models of international collaboration. This is no coincidence; it is the natural resu